J. Donald Ostrow, M.D., F.A.C.P.; Carl A. Mulvansy, M.D.; John R. Hansell, M.D.
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Three chemical tests for fecal occult blood were compared on stools collected from 20 healthy, nonbleeding volunteers, before
and after intragastric instillation of 51Cr-labeled red cells ("blood"). Subjects maintained a meat-free diet for 5 days before and 7 days after 51Cr RBC were given. Well-counting of fecal radioactivity provided an accurate measurement of fecal hemoglobin content against which to gauge the chemical tests. Reproducibility was determined by having two experienced observers independently perform each test on the same stool specimens on the same day and by retesting each stool after storage at 4°C for 5 to 8 days. The results
Ostrow JD, Mulvansy CA, Hansell JR. Sensitivity and Reproducibility of Guaiac, Hematest, and Hemoccult Test for Fecal Occult Blood.. Ann Intern Med. ;76:860–861. doi: 10.7326/0003-4819-76-5-860_4
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Published: Ann Intern Med. 1972;76(5):860-861.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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