Corwin R. Dunn, M.D.; James S. Tan, M.D.; John P. Shair, M.D.
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Gram-negative organisms have been implicated as the causative agent in 5 to 10% of cases of endocarditis. Up to one half of reported cases, however, represented infected prosthetic valves; the remainder were not described as a separate entity. Twelve cases seen at the University of Cincinnati Medical Center, including three discovered at autopsy, were reviewed. None of the cases were in drug addicts. Diagnosis was based on antemortem blood cultures or clinical or autopsy findings. These cases represent approximately 6% of the patients with endocarditis seen during 1946-71. Causative bacteria included Escherichia coli (3), Enterobacter (3), Actinobacillus (2), Proteus mirabilis
Dunn CR, Tan JS, Shair JP. Gram-Negative Endocarditis in Patients without Cardiac Prosthetic Valves.. Ann Intern Med. 1972;76:863. doi: 10.7326/0003-4819-76-5-863_1
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Published: Ann Intern Med. 1972;76(5):863.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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