Harry Lipp, M.B.B.S.; Pablo Denes, M.D.; Miguel Gambetta, M.D.; Leon Resnekov, M.D.
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Eight patients with acute myocardial infarction, three not in failure and five in moderate or severe clinical or hemodynamic failure, were investigated after the intravenous administration of 0.5 to 0.75 mg digoxin. Mean aortic pressure (Ao), mean pulmonary arterial pressure (PA), left ventricular filling pressure (LVFP), cardiac index (CI), stroke index (SI), arterial PO2, pulmonary arterial oxygen saturation (pulmonary arterial So2), systemic vascular resistance (SVR), left ventricular stroke work index (LVSWI), left ventricular minute work index (LVMWI), and tension time index (TTI) were obtained before and 1 hour after intravenous digoxin. Patients in moderate or severe failure had significant changes
Lipp H, Denes P, Gambetta M, Resnekov L. Hemodynamic Effects of Intravenous Digoxin in Acute Myocardial Infarction.. Ann Intern Med. ;76:865–866. doi: 10.7326/0003-4819-76-5-865_4
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Published: Ann Intern Med. 1972;76(5):865-866.
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