Emmanuel C. Besa, M.D.; Dov Gorshein, M.D.; Frank H. Gardner, M.D., F.A.C.P.
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High doses of androgens have increased hemoglobin concentration in patients and animals. Verwilghen and associates demonstrated a fall in plasma volume in nonhematologic patients treated with nandrolane, 25 mg/month for 1 to 3 years. They attributed the rise in hematocrit to hemoconcentration. A later study by Gardner and colleagues, using testosterone enanthate, 800 mg weekly for 6 weeks, increased the red cell mass and plasma volume in 15 elderly normal men. We have studied blood volume changes, using nandrolone decanoate, 3 mg/kg body weight·week. Blood volume was measured with 51Cr-labeled RBCs before therapy as well as after 5 weeks, 10
Besa EC, Gorshein D, Gardner FH. Blood Volume Changes in Normal and Various Anemic States in Man After Androgen Administration.. Ann Intern Med. ;76:869. doi: 10.7326/0003-4819-76-5-869_1
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Published: Ann Intern Med. 1972;76(5):869.
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