P. McPhedran, M.D.; M. G. Barnes, M.D.; J. Weinstein, M.D.
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This study was made to furnish statistical information to aid in the interpretation of abnormal mean corpuscular volumes, detected by the Model S Coulter Counter. No systematic study of the meaning of an abnormal MCV has been made since accurate red cell sizing became routinely available. Although an abnormal MCV is known to be a useful clue to diagnosis in severely anemic patients, its usefulness in other patients has scarcely been studied. Patients with mean corpuscular volumes of 115 or greater and 75 or less, regardless of hematrocrit level, were selected for study. Patients with macrocytosis had plasma B12 and
McPhedran P, Barnes MG, Weinstein J. Differential Diagnosis of the Abnormal Mean Corpuscular Volume (MCV).. Ann Intern Med. ;76:869–870. doi: 10.7326/0003-4819-76-5-869_3
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Published: Ann Intern Med. 1972;76(5):869-870.
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