Robert M. Gipstein, M.D.; Donald A. Adams, M.D., F.A.C.P.; Jack W. Coburn, M.D., F.A.C.P.
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Two recent reports have indicated that necrotizing skin and digital lesions may occur in association with the secondary hyperparathyroidism of chronic renal disease. Two such instances were seen. The first was in a 22-year-old white woman with chronic glomerulonephritis who, 14 months after receiving a renal transplant, developed patchy, necrotizing skin lesions in both lower legs at a time when most serum calcium determinations were at the upper limit of normal. Subtotal extirpation of four hyperplastic parathyroid glands lead to slow healing of the lesions. Serum parathormone levels are pending. Serum calcium determinations have fallen to low normal values. The
Gipstein RM, Adams DA, Coburn JW. Ischemic Vascular Necrosis Associated with Uremic Hyperparathyroidism.. Ann Intern Med. ;76:874. doi: 10.7326/0003-4819-76-5-874_1
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Published: Ann Intern Med. 1972;76(5):874.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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