W. Dallas Hall, M.D.; Robert A. Hatcher, M.D.
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A controlled and longitudinal study was instituted to ascertain the frequency of hypertension associated with use of oral contraceptives.
One hundred and ninety 6-weeks postpartum negro women were enrolled in this ongoing study. Contraception was initiated with either Ovulen-21® (1.0 mg ethynodiol diacetate and 0.1 mg mestranol) or an intrauterine device (IUD). Thrice-repeated, supine, right arm systolic (S) and Phase V diastolic (D) measurements were made by the same observer at 6 (baseline), 18, and 30 weeks postpartum. Thus far, 80 women have completed a minimum of 30 weeks follow-up.
Women on oral contraceptives developed a 5.0-mm Hg rise in
Hall WD, Hatcher RA. The Frequency of Hypertension Induced by Oral Contraceptives.. Ann Intern Med. ;76:874. doi: 10.7326/0003-4819-76-5-874_2
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Published: Ann Intern Med. 1972;76(5):874.
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