Michael J. Kinney, M.D.; Stafford Cohen, M.D.; Richard Stein, M.D.; Sun Lau, M.D.; Anthony Damato, M.D.; Vincent DiScala, M.D.
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Two patients with the clinical syndrome of polyuria and paroxysmal atrial tachycardia underwent renal clearance studies during their diureses. One of them excreted 263 mEq Na+ in 1833 ml of urine and the other (on a salt-restricted diet), 42 mEq Na+ and 1357 ml. Both polyuric episodes were characterized by salureses with the formation of concentrated urine in one patient and dilute urine in the other. Glomerular filtration rate (GFR) and renal blood flow were relatively unchanged. The increased sodium excretion was caused by decreased renal tubular sodium reabsorption, probably at proximal tubular nephron sites. Reevaluation of earlier case reports
Kinney MJ, Cohen S, Stein R, Lau S, Damato A, DiScala V. The Renal Effects of Paroxysmal Atrial Tachycardia and Atrial Pacing Tachycardia.. Ann Intern Med. ;76:874–875. doi: 10.7326/0003-4819-76-5-874_4
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Published: Ann Intern Med. 1972;76(5):874-875.
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