I. R. Collmann, M.D.; R. D. Lange, M.D., F.A.C.P.; A. I. Chernoff, M.D., F.A.C.P.; T. A. Jordan, M. T.
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This study was undertaken to determine the utilization of the hemagglutination inhibition test for the presence of carcinoembryonic antigen in the sera of patients with entodermally derived malignancies and other nonneoplastic conditions. Antisera to malignant colonic tissue and normal colon was prepared by immunization of rabbits over a 4-week period. The results so far are from approximately 400 patients, and all 46 patients who had entodermally derived neoplasia had positive titers for carcinoembryonic antigen. Nonneoplastic conditions such as cirrhosis of the liver, chronic ulcerative colitis, and regional enteritis in this series had about a 45% incidence of positive titers. Out
Collmann IR, Lange RD, Chernoff AI, Jordan TA. Experience with a Hemagglutination-lnhibition Test for Carcinoembryonic Antigen.. Ann Intern Med. ;76:876. doi: 10.7326/0003-4819-76-5-876_3
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Published: Ann Intern Med. 1972;76(5):876.
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