R. S. Pascual, M.D.; P. E. Perillie, M.D.; S. Sulavik, M.D.; J. A. Donadio, M.D.; J. B. L. Gee, M.D., F.A.C.P.; S. C. Finch, M.D.
This content is PDF only. Please click on the PDF icon to access.
The clinical significance of lysozymuria and increased serum lysozyme activity was evaluated in 41 patients with proved sarcoid. Lysozyme activity was determined by either the lysoplate or turbidimetric method. All patients were staged according to chest radiographic findings. Most had total and differential white cell counts, blood urea nitrogen, and serum calcium determinations. Lysozymuria was present in 15 of 41 patients (37%), and lysozyme activity was increased in 14 of 23 (61%). All five patients with obvious splenic involvement had increased lysozyme activity. All patients with increased activity had early infiltrative lung disease with hilar adenopathy. Successful corticoid therapy was
Pascual RS, Perillie PE, Sulavik S, Donadio JA, Gee JBL, Finch SC. Lysozyme Studies in Sarcoidosis.. Ann Intern Med. ;76:880. doi: 10.7326/0003-4819-76-5-880_3
Download citation file:
Published: Ann Intern Med. 1972;76(5):880.
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use