Joseph L. Hollander, M.D., F.A.C.P.; Arnold J. Rawson, M.D.; Francisco J. Tapanes, M.D.
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The clinical similarities and differences between rheumatoid and psoriatic arthritis are well known. Patients with psoriatic arthritis are seronegative for rheumatoid factor, but so also are one fifth of those with classical rheumatoid arthritis and nearly all those with juvenile rheumatoid arthritis when the usual latex or sheep-cell tests are used. Using the newer methods for quantifying antigammaglobulins by immunoadsorption to cross-linked IgG, elution with acid buffer, and radial immunodiffusion, it has been shown that almost all sera and joint fluids from active but seronegative juvenile or adult rheumatoids exhibit significantly elevated amounts of anti-immunoglobulin, mainly of IgG type.
Hollander JL, Rawson AJ, Tapanes FJ. Immunologic Differences Between Psoriatic and Rheumatoid Arthritis.. Ann Intern Med. ;76:881. doi: 10.7326/0003-4819-76-5-881_2
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Published: Ann Intern Med. 1972;76(5):881.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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