WILLIS C. MADDREY, M.D.; HARRY F. KLINEFELTER, M.D.
To the editor: The rapid appearance of scrotal and peripheral edema after abdominal paracentesis, as described by Conn in the ANNALS OF INTERNAL MEDICINE (1), was seen in a patient after percutaneous peritoneal biopsy. Of particular interest was the concomitant occurrence of an impressive diuresis, beginning within hours of the biopsy.
The patient, a 37-year-old man—a laborer, chronic alcoholic, and heroin user— was studied for persistent massive ascites, which was treated unsuccessfully for 2 months with salt and water restriction, spironolastone (Aldactone®; up to 150 mg/day), and furosenide (Lasix®; up to 240 mg/day). The elevated ascitic-fluid protein (2.5 to 3.4
MADDREY WC, KLINEFELTER HF. Edema and Diuresis from Peritoneal Biopsy. Ann Intern Med. ;76:1044. doi: 10.7326/0003-4819-76-6-1044_1
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Published: Ann Intern Med. 1972;76(6):1044.
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