SYANIAL K. DATTA, M.D.
To the editor: In their recent article (1) Aberman and Fulop describe multiple factors in pulmonary edema that can cause hypercapnia. They postulate that these factors act by influencing the well-known equation (2), alveolar PCO2 = K· VCO2/VA where VCO2 is carbon dioxide output, VA is alveolar ventilation, and K is a constant. This equation shows that if the alveolar ventilation is halved, the alveolar (and therefore arterial) PCO2 is doubled, other factors being constant. This equation assumes that mixed alveolar and mixed arterial PCO2S are equal and can be applied to a single lung unit or a homogeneous normal
DATTA SK. Blood Gases in Pulmonary Edema. Ann Intern Med. ;76:1045–1046. doi: 10.7326/0003-4819-76-6-1045
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Published: Ann Intern Med. 1972;76(6):1045-1046.
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