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The goal of Dr. Aikawa, a well-known worker in the field of magnesium metabolism, was to summarize current knowledge in the anatomy, biochemistry, physiology, and pathophysiology of magnesium. In addition, he presents an argument for his hypothesis that the single mechanism of action of magnesium in all biological processes is that of a chelating agent.
An excellent, although selected, summary of magnesium metabolism is presented in a brief, easy-to-read text. The first chapter, "A General Hypothesis Concerning the Biochemical and Cellular Functions of Magnesium," is so sketchy and some of the material so basic that the "basis" of his hypothesis
The Relationship of Magnesium to Disease in Domestic Animals and in Humans.. Ann Intern Med. ;76:1056. doi: 10.7326/0003-4819-76-6-1056_1
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Published: Ann Intern Med. 1972;76(6):1056.
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