JOEL SPRAGINS, M.D.; W. H. HALL, M.D.; H. J. WHITE, M.D.
To the editor: The recent editorials of Gordan and Roof (1) and Kraft (2), "Humors from Tumors," made several points regarding the finding, in patients with malignant neoplasms, of hormones and circulating proteins that are usually characteristic of human fetus ("fetospecific"). One of their points was to anticipate the finding of patients with multiple fetospecific humors.
We have observed a case of squamous cell carcinoma of the esophagogastric junction, with undifferentiated metastasis in the liver at autopsy. The patient was found to have alpha-fetoprotein in his serum on two of four occasions by agarose immunodiffusion and to have the fetal
SPRAGINS J, HALL WH, WHITE HJ. Fetoprotein from Esophageal Squamous Cell Carcinoma. Ann Intern Med. ;77:322–323. doi: 10.7326/0003-4819-77-2-322_2
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Published: Ann Intern Med. 1972;77(2):322-323.
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