PHILIP E. CRYER, M.D.
To the editor: The measurement of bilateral renal-vein plasma renin activity has been used to select hypertensive patients with anatomic renal artery stenosis for surgical therapy. Ratios of renin in the two renal veins of 1.5:1 or greater have been considered positive; however, persistent hypertension (diastolic pressure of 90 mm Hg or greater) has been reported in 14% to 50% of such patients after corrective surgery (1-5). Persistent hypertension may be owing to either failure to restore adequate flow to the ischemic kidney or to diagnostic error. The latter is not unexpected. First, the finding of renal-vein plasma renin activity
CRYER PE. Acquired Renal Artery Stenosis and a Positive Renal-Vein Renin Ratio. Ann Intern Med. ;77:478–479. doi: 10.7326/0003-4819-77-3-478
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Published: Ann Intern Med. 1972;77(3):478-479.
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