ROGER W. JELLIFFE, M.D.; DANIEL IVLER, PH.D.
To the editor: The article by Chan, Benner, and Hoeprich, describing their nomogram for gentamicin dosage in patients with renal insufficiency ( 1 ), was read with interest. Their nomogram is useful, and the data seem to be solid. Their discussion, however, might have been enhanced by a more complete reference to similar work done by others. For example, probably the first description of the relationship between the kinetic properties of drugs and proper dosage regimens was done by Augsberger for cardiac glycosides (2). This approach was refined and extended by the late Ekkehard Kruger-Thiemer into a formal theory of
JELLIFFE RW, IVLER D. Gentamicin and Kanamycin Nomograms. Ann Intern Med. ;77:480–481. doi: 10.7326/0003-4819-77-3-480
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Published: Ann Intern Med. 1972;77(3):480-481.
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