MEYER D. LIFSCHITZ, M.D.
To the editor: The paper by Weidmann and colleagues, "Blood Pressure Effects of Acute Hypercalcemia" (1), documents without question the reproducibility of this phenomena but leaves open for discussion the mechanism by which an increase of serum calcium leads to a rise in blood pressure. The authors suggest that this effect is probably due to an increase in peripheral vascular resistance.
This increase has been documented in the literature. Maxwell, Elliott, and Robertson (2) studied 10 anesthetized dogs and measured cardiac output during a calcium infusion. They found that blood pressure rose in their animals at a time when cardiac
LIFSCHITZ MD. Serum Calcium and Peripheral Resistance. Ann Intern Med. ;77:482. doi: 10.7326/0003-4819-77-3-482_1
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Published: Ann Intern Med. 1972;77(3):482.
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