DAVID R. MUSHER, M.D.
To the editor: I read with interest the article, "Pleural Fluid Complement in Systemic Lupus Erythematosus and Rheumatoid Arthritis," by HUNDER, MCDUFFIE, and HEPPER (Ann Intern Med 76:357-363, 1972). The article is important because it is one of several that help us to distinguish the causes of effusions in collagen diseases. We have seen patients with lupus peritonitis who had positive LE preparations and four-plus peripheral pattern antinuclear antibodies in paracentesis fluids. These findings were not unexpected; the patients were afflicted with an active systemic disease.
To elucidate the causes of lowered complement levels and the interrelation between serum and
MUSHER DR. Pleural Fluid Complement. Ann Intern Med. ;77:482–483. doi: 10.7326/0003-4819-77-3-482_3
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Published: Ann Intern Med. 1972;77(3):482-483.
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