RONALD I. CANTOR, M.D.; GEORGE E. DOWNS, Pharm. D.; JOHN L. ABRUZZO, M.D.
An acute exacerbation of spondylitis developed after an intravenous infusion of iron dextran in a 49-year-old patient with known ankylosing spondylitis. The acute inflammatory reaction seems analogous to that observed recently in rheumatoid arthritis. Underlying arthritis of a nonspecific nature may be a necessary requirement for the iron-induced reaction (which may be owing to the effect of iron on pyrophosphatase) to occur.
CANTOR RI, DOWNS GE, ABRUZZO JL. Acute Exacerbation of Ankylosing Spondylitis After an Iron Dextran Infusion. Ann Intern Med. ;77:933–934. doi: 10.7326/0003-4819-77-6-933
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Published: Ann Intern Med. 1972;77(6):933-934.
Infectious Disease, Rheumatology.
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