MICHAEL L. LEVIN, M.D.
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To the editor: The article in the July 1972 issue of the ANNALS OF INTERNAL MEDICINE, "Serious Infection After Splenectomy for the Staging of Hodgkin's Disease", comments that splenectomized patients, especially children, should be given prophylactic doses of penicillin for 2 years after splenectomy. The reference cited, "Relation Between Splenectomy and Subsequent Infection. A clinical study," by Horan and Colebatch, is a decade old. I question whether penicillin prophylaxis for 2 years is the optimal choice of therapy for such patients at present.
Markowitz and Kuttner, in their book Rheumatic Fever Diagnosis, Management and Prevention, page 180, have shown how
LEVIN ML. Penicillin After Splenectomy?. Ann Intern Med. ;77:1002. doi: 10.7326/0003-4819-77-6-1002_1
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Published: Ann Intern Med. 1972;77(6):1002.
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