HAROLD J. HARRIS, M.D., F.A.C.P.
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To the editor: No longer is there available an antigen for intradermal testing or the desensitization of patients with chronic brucellosis.
This poses a serious problem. No other case-finding method is so important as the intradermal test done with a suitable antigen. The value of the skin test in case finding is exactly comparable to tuberculin testing in suspected tuberculosis. Nor is there any effective treatment for chronic brucellosis, other than desensitization with an effective antigen; antibiotics have limited, if any, value in this phase of brucella infection and its allergic manifestations. Agglutinins are seldom present in the serum of
HARRIS HJ. Brucella Antigen. Ann Intern Med. ;78:302. doi: 10.7326/0003-4819-78-2-302_1
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Published: Ann Intern Med. 1973;78(2):302.
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