MATHIOS CONSTANTOULAKIS, M.D., PH.D.; PANAYOTIS ECONOMOPOULOS, M.D.; ATHANOSIOS CONSTANTOPOULOS, M.D.
To the editor: In a recent editorial in your journal (Ann Intern Med 77:143-146, 1972), Desser and Ultmann emphasize the increased risk of severe infections after splenectomy for Hodgkin's disease or lymphoma. In their review of the literature they point out an increased incidence of postsplenectomy infections in various other diseases, especially homozygous β-thalassemia. In our experience the incidence of severe infections after splenectomy in β-thalassemia is much lower than the 20% to 30% of cases mentioned in the editorial. In 72 splenectomized thalassemic patients (with an age range of 5 to 15 years at the time of the operation)
CONSTANTOULAKIS M, ECONOMOPOULOS P, CONSTANTOPOULOS A. Infections After Splenectomy. Ann Intern Med. ;78:780–781. doi: 10.7326/0003-4819-78-5-780_2
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Published: Ann Intern Med. 1973;78(5):780-781.
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