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Despite the development of biochemical, immunological, tissue culture, genetic, and physiological methods in hematology, the diagnostic value of purely morphological methods cannot be underestimated. Most clinically oriented American hematologists rely heavily on bone marrow aspiration with examination of Wright-Giemsa smears. Many pathologists, however, prefer to interpret fixed tissue sections because they preserve architectural relationships and give a better picture of the organizational quality of bone marrow than do smears. Although examination of smears may suffice for most routine clinical situations, one cannot deny that there are specific hematologic lesions that can be far better examined with fixed tissue sections. Logically,
Bone Marrow and Bone Tissue. Color Atlas of Clinical Histopathology.. Ann Intern Med. ;78:803–804. doi: 10.7326/0003-4819-78-5-803_2
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Published: Ann Intern Med. 1973;78(5):803-804.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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