Frank Rees Smith, M.D.; John Lindenbaum, M.D.
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Plasma vitamin A concentrations are widely used to screen for malabsorption. Isolation and characterization of the proteins responsible for plasma vitamin A transport in man—retinol-binding protein and prealbumin—has made it possible to explore the regulation of plasma vitamin A concentration in patients with impaired absorption. Concentrations of retinol-binding protein and prealbumin were measured by immunoassays in 22 adults with malabsorption (postgastrectomy, 5; chronic pancreatitis, 3; celiac sprue, 5; tropical sprue, 4; Zollinger - Ellison syndrome, 2; regional iletis, 1; postileal resection, 2) who had normal hepatic and renal function. During active malabsorption (mean stool fat, 23 g/72 hr; range, 8
Smith FR, Lindenbaum J. Human Plasma Retinol Transport in Malabsorption.. Ann Intern Med. ;78:817–818. doi: 10.7326/0003-4819-78-5-817_4
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Published: Ann Intern Med. 1973;78(5):817-818.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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