S. D. Shappell, M.D., F.A.C.P.; Charles E. Marshall, M.D.; Ross E. Brown, M.D.; Thomas A. Bruce, M.D., F.A.C.P.
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The propositus, a 27-year-old white woman, had experienced five syncopal episodes since age 13. During excitement, she suffered cardiac arrest and was successfully resuscitated from ventricular fibrillation. Although her cardiovascular status was stable, she remained apneic and in coma. Her mother and grandmother had both died sudden, unexpected deaths when 32 and 40 years old, respectively. Examination at admission showed midsystolic click and late systolic murmur. Brain scan and EEG were negative. An ECG showed inverted T waves in leads II, III, aVF, and a QTc interval of 0.47 seconds. Control of cerebral edema led to ultimate restoration of near-normal
Shappell SD, Marshall CE, Brown RE, Bruce TA. Sudden Death and Familial Occurrence of Midsystolic Click-Late Systolic Murmur Syndrome.. Ann Intern Med. ;78:819. doi: 10.7326/0003-4819-78-5-819_2
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Published: Ann Intern Med. 1973;78(5):819.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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