Dennis G. Maki, M.D.; Donald A. Goldmann, M.D.; Frank S. Rhame, M.D.; John V. Bennett, M.D.
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Between summer 1970 and March 1971, 394 patients in 25 hospitals in the United States experienced 412 episodes of nosocomial Gram-negative septicemia while receiving intravenous (IV) infusion products from one manufacturer. The epidemic was traced by the Center for Disease Control to intrinsic contamination of a newly introduced screw cap for the infusion bottles. In our investigations many new clinical and microbiologic observations were found to be applicable to the prevention of intravenous-associated septicemia.
1. These septicemias are clinically indistinguishable from those of other causes except that patients with these infections frequently have no underlying predisposing diseases or overt sites
Maki DG, Goldmann DA, Rhame FS, Bennett JV. Infection Control in Intravenous Therapy.. Ann Intern Med. ;78:825. doi: 10.7326/0003-4819-78-5-825_2
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Published: Ann Intern Med. 1973;78(5):825.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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