Bernadine H. Bulkley, M.D.; William C. Roberts, M.D.
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Although aortic regurgitation has been described previously in patients with ankylosing spondylitis, the distinctive morphologic features of the cardiovascular lesion have not been defined. All eight patients had combined spondylitis and aortic regurgitation; one also had Reiter 's syndrome. All were men (age, 34-55 years), all had severe congestive heart failure, and all had evidence of joint involvement consistent with ankylosing spondylitis. Six had conduction disturbances. All died at an average of 6 years after the onset of congestive heart failure. In at least three patients signs of valvular dysfunction (murmur) antedated or coincided with the earliest arthritic symptoms. The
Bulkley BH, Roberts WC. The Distinctive Cardiovascular Lesion of Ankylosing Spondylitis: A Study of 8 Necropsy Patients.. Ann Intern Med. 1973;78:834. doi: 10.7326/0003-4819-78-5-834_1
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Published: Ann Intern Med. 1973;78(5):834.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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