WILLIAM R. SALYER, M.D.; DIANE C. SALYER, M.D.; ROBERT H. HEPTINSTALL, M.D.
Microangiopathic hemolytic anemia was found in 7 of 20 patients with systemic scleroderma, an indication that this complication is not uncommon. Since only four had severe hypertension, pressures in the "malignant" range seem not to be necessary for the development of the anemia. All seven patients had renal arterial fibrin deposits, which supports the concept that erythrocyte fragmentation results from contact with intravascular fibrin.
SALYER WR, SALYER DC, HEPTINSTALL RH. Scleroderma and Microangiopathic Hemolytic Anemia. Ann Intern Med. 1973;78:895–897. doi: 10.7326/0003-4819-78-6-895
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Published: Ann Intern Med. 1973;78(6):895-897.
Hematology/Oncology, Red Cell Disorders, Rheumatology, Scleroderma.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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