ABRAHAM P. ZIMELMAN, M.D.
To the editor: In multiple myeloma the platelet count is usually normal or decreased (1). Thrombocytosis is unusual. This report describes three cases of multiple myeloma associated with thrombocytosis.
Patient 1, a 63-year-old man, presented with a 24-hour history of shaking chills. On physical examination he had a temperature of 38.9 °C [102 °F], rales in both bases, and an apical systolic murmur. Laboratory studies showed the following values: hemogloblin, 7.6 g/100 ml; hematocrit, 22; leukocyte count, 15 000/mm3, with a normal differential; and platelet count, 800 000/mm3 (2). Blood smear showed rouleau formation and increased platelets (Figure 1A). Serum
ZIMELMAN AP. Thrombocytosis in Multiple Myeloma. Ann Intern Med. ;78:970–971. doi: 10.7326/0003-4819-78-6-970
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Published: Ann Intern Med. 1973;78(6):970-971.
Hematology/Oncology, Multiple Myeloma, Platelet Disorders.
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