CARL B. LAUTER, M.D.; M. RIAD EL KHATIB, M.D.; JAMES A. RISING, M.D.; ERWIN ROBIN, M.D., F.A.C.P.
The nitroblue tetrazolium dye test was evaluated in 16 patients with acute myocardial infarction, a stressful, noninfectious disease. All subjects had positive tests during the acute phase of their illness. Over a 2-week period the values fell into the control range in 7 of 10 patients who were serially tested. Three patients who developed complications had persistently positive tests. There was no correlation between the test and fever, total leukocyte count, or myocardial enzyme values. Anticoagulant therapy did not seem to affect the results. Neutrophil activation was thus shown in patients with acute myocardial infarction. This activation was related to the age of the infarction and seemed to correlate with the stages of maximal neutrophilic infiltration in the damaged areas.
LAUTER CB, EL KHATIB MR, RISING JA, ROBIN E. The Nitroblue Tetrazolium Test and Acute Myocardial Infarction: A Study in Patients. Ann Intern Med. 1973;79:59–62. doi: 10.7326/0003-4819-79-1-59
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Published: Ann Intern Med. 1973;79(1):59-62.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Emergency Medicine.
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