CHARLES K. TASHIMA, M.D.
To the editor: The recent reports (1-3) on the causes of elevated creatine phosphokinase (CPK) in noncardiac conditions call for emphasis on its occurrence in many different situations.
Levitan's case (1) of elevated CPK in an alcoholic who developed acute pancreatitis and lactic acidosis while on phenformin therapy made me recall two patients with puzzling increases of CPK. Both patients were known alcoholics prone to alcohol binges. The CPK levels were elevated 8 to 16 times the normal values and remained elevated for many days after admission. After numerous studies in one of these patients, which included endocrine, neuromuscular, and
TASHIMA CK. Creatine Phosphokinase Elevation. Ann Intern Med. ;79:140. doi: 10.7326/0003-4819-79-1-140_1
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Published: Ann Intern Med. 1973;79(1):140.
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