A. MARTIN LERNER, M.D.; CARL B. LAUTER, M.D.; DAVID C. NOLAN, M.D.
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To the editor: We would like to remark on the comment to the Editor in the May issue (Ann Intern Med 78:779, 1973), by Hirsch, Levin, and Chien, related to our recent article (Ann Intern Med 78:243-246, 1973) concerning experience with idoxuridine in 29 cases of herpes simplex virus encephalitis studied by us from 1966 to 1971. We quote from the letter of Hirsch and colleagues: "little appears to be gained by further publication of uncontrolled studies or case reports of various modes of therapy in this disorder." Hirsch properly indicates that "two controlled randomized multicenter studies on the role
LERNER AM, LAUTER CB, NOLAN DC. Herpes Simplex Virus Encephalitis: Therapy Trials. Ann Intern Med. ;79:285. doi: 10.7326/0003-4819-79-2-285_2
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Published: Ann Intern Med. 1973;79(2):285.
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