LEON M. PROTASS, M.D.
To the editor: A 2- to 4-minute period of voluntary hyperventilation during electroencephalography is a benign provocative procedure, of limited value, done in most laboratories. This is a report of a presumed adverse reaction in a child with sickle cell disease.
An 11-year-old girl with sickle-cell disease had had episodes of left hemiparesis 1½ and 4 months earlier. On both occasions there was complete resolution of the paresis within a few days, but a left homonymous hemianopsia persisted after the second episode. Cerebral vascular thrombosis was thought to be the cause (1). A routine electroencephalogram was done. Immediately after hyperventilation,
PROTASS LM. Possible Precipitation of Cerebral Thrombosis in Sickle-Cell Anemia by Hyperventilation. Ann Intern Med. ;79:451. doi: 10.7326/0003-4819-79-3-451_1
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Published: Ann Intern Med. 1973;79(3):451.
Hematology/Oncology, Red Cell Disorders.
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