ROGER W. JELLIFFE, M.D.
To the editor: Previously described computer programs have shown their ability to estimate endogenous creatinine clearance (Ccr) with reasonable accuracy when urine specimens cannot be obtained to calculate endogenous creatinine clearance in the standard manner (1). Such estimates have been very useful for planning drug dosage regimens for patients (2, 3) : they have been based on stable or changing serum creatinine levels, age, sex, height, and weight.
When the serum creatinine level is stable, however, and the patient is an adult from 20 to 80 years old, a bedside estimate that closely approaches those of the computer programs may
JELLIFFE RW. Creatinine Clearance: Bedside Estimate. Ann Intern Med. ;79:604–605. doi: 10.7326/0003-4819-79-4-604
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Published: Ann Intern Med. 1973;79(4):604-605.
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