CARROLL M. LEEVY, M.D.; ROWEN ZETTERMAN, M.D.
During the past decade, much progress has been made in understanding the pathobiology of alcoholic hepatitis. Prospective natural history studies indicate that 80% of patients with this lesion who continue to drink develop cirrhosis within 5 years (1); this is consistent with the finding that ethanol causes increased in-vitro incorporation of tritiated proline into collagen of biopsy specimens of alcoholic hepatitis (2). Alcoholic hepatitis occurs in only 10% to 30% of patients with a history of chronic alcoholism in which intake of alcoholic beverages is sufficient to interfere with work, social responsibilities, and proper food intake. This variation in susceptibility
CARROLL M. LEEVY, ROWEN ZETTERMAN. Alcoholic Hepatitis and Corticosteroids. Ann Intern Med. 1973;79:739–740. doi: 10.7326/0003-4819-79-5-739
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Published: Ann Intern Med. 1973;79(5):739-740.
Gastroenterology/Hepatology, Liver Disease, Tobacco, Alcohol, and Other Substance Abuse.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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