THEODORE L. BADGER, M.D.
To the editor: In the editorial by Stead and Texter, "Isoniazid Hepatitis: Backlash of Progress," in the ANNALS OF INTERNAL MEDICINE, 79:125-127, 1973, the advice for supervising patients taking isoniazid prophylactically or for treatment is sound and judicious.
It is of interest, however, that the liver is much like the lung in one respect; its similar pathologic response to various insults. The U.S. Public Health Service report on nationwide studies of hepatitis associated with the use of isoniazid showed a high morbidity and mortality only in Washington, D.C., and Baltimore, Maryland. In both places other factors of chronic disease were
BADGER TL. Isoniazid Hepatitis. Ann Intern Med. ;79:751–752. doi: 10.7326/0003-4819-79-5-751
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Published: Ann Intern Med. 1973;79(5):751-752.
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