PRADEEP CHANDRA, M.D.; FRED ROSNER, M.D., F.A.C.P.; ARTHUR SAWITSKY, M.D., F.A.C.P.
To the editor: Sea-blue histiocytes have been found in the bone marrow of patients with the hereditary syndrome (1), as well as that of patients with other disorders—chronic granulocytic leukemia (2), polycythemia vera (3), erythremic myelosis (4), sickle-cell disease (5), hypochromic anemia (3), Hurler's syndrome (3), rheumatoid arthritis (3), Hodgkin's disease1 and multiple myeloma1—and even in two of 14 healthy rabbits (6). We have recently seen a patient with autoimmune thrombocytopenic purpura who had sea-blue histiocytes in her marrow aspirate when her platelet count was 3000/mm3; these histiocytes were not seen when the disease was in remission.
A 22-year old
CHANDRA P, ROSNER F, SAWITSKY A. Sea-Blue Histiocytes in Thrombocytopenic Purpura. Ann Intern Med. ;79:901–902. doi: 10.7326/0003-4819-79-6-901
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Published: Ann Intern Med. 1973;79(6):901-902.
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