RONALD D. ADLER, M.D.
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To the editor: In their paper describing the use of transfer factor to reverse the downhill course of a patient with progressive primary tuberculosis (Ann Intern Med 79:161-166, 1973), Whitcomb and Rocklin did not discuss the possible role of corticosteroid administration and withdrawal in the course of the illness. Indeed, the patient reverted from tuberculin-positive to negative after initiation of steroid therapy, whereas the return of skin-test reactivity and clinical improvement, which was attributed to transfer factor administration, coincided with steroid withdrawal.
As a nonspecialist I would appreciate a comment from the authors on the relations among corticosteroid treatment, transfer
ADLER RD. Steroids, Transfer Factor, and Tuberculosis. Ann Intern Med. ;79:910–911. doi: 10.7326/0003-4819-79-6-910_2
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Published: Ann Intern Med. 1973;79(6):910-911.
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