DONATO ALARCÓN-SEGOVIA, M.D., F.A.C.P.; EUGENIA FISHBEIN; JOHN L. ABRUZZO, M.D., F.A.C.P.; RALPH HEIMER, Ph.D.
Two patients had Sjögren's syndrome and chronic polysynovitis that had caused neither deformity nor bony erosions. Both patients had increased serum viscosity, and one patient had the hyperviscosity syndrome. Increased serum viscosity correlated with the presence of intermediate complexes that seem to be formed by interactions between IgG antigen and IgG rheumatoid factor. Neither the occurrence of the hyperviscosity syndrome in Sjögren's syndrome nor the association of hyperviscosity with circulating serum IgG-IgG rheumatoid factor complexes has been previously reported.
ALARCÓN-SEGOVIA D, FISHBEIN E, ABRUZZO JL, HEIMER R. Serum Hyperviscosity in Sjögren's Syndrome: Interaction Between Serum IgG and IgG Rheumatoid Factor. Ann Intern Med. ;80:35–43. doi: 10.7326/0003-4819-80-1-35
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Published: Ann Intern Med. 1974;80(1):35-43.
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