W. PRUZANSKI, M.D., F.R.C.P.(C.), F.A.C.P.
In the coming era of computerized medicine and automated science, there will still be a place for old-fashioned clinical observations. New clinical syndromes are still being discovered, and old ones are being redefined by new scientific knowledge.
The clinical manifestations of blood hyperviscosity in macroglobulinemia and multiple myeloma were described many years ago (1, 2). Hyperviscosity in these two diseases is caused by a very high concentration of an M component in the serum, by aggregation of or by high intrinsic viscosity of the immunoglobulin molecules. In other diseases, such as polycythemia, thrombocythemia, or leukemia, hyperviscosity results from an abnormally
PRUZANSKI W. Hyperviscosity and Immunoglobulin Complexes. Ann Intern Med. 1974;80:107. doi: 10.7326/0003-4819-80-1-107
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Published: Ann Intern Med. 1974;80(1):107.
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