EDWARD B. SILBERSTEIN, M.D., F.A.C.P.; DAVID C. ZELLNER, M.D., F.A.C.P.; BAVIKATTE N. SHIVAKUMAR, M.D.; LEONARD A. BURGIN, M.D.
To the editor: Marked peripheral blood leukocytosis without immature forms in the peripheral blood leads the clinician to search for occult infection or other causes of a "leukemoid" reaction. We report here the clinical and pathologic data on such a patient, who proved to have "pure" neutrophilic leukemia. This is only the third such case, with bone-marrow chromosome study results, to be reported.
The patient, a 75-year-old white woman, was hospitalized in January 1971 for splenomegaly and painful compression fractures of the D 12, L 1 and L 2 vertebrae. The leukocyte count was 45 000/mm3 (88% were mature polymorphonuclear
SILBERSTEIN EB, ZELLNER DC, SHIVAKUMAR BN, BURGIN LA. Neutrophilic Leukemia. Ann Intern Med. ;80:110–111. doi: 10.7326/0003-4819-80-1-110
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Published: Ann Intern Med. 1974;80(1):110-111.
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