NORMAN D. OLSON, M.D.
To the editor: In The October Issue (Ann Intern Med 79:551-554, 1973) Dubovsky and associates reported the syndrome of inappropriate secretion of antidiuretic hormone associated with an acute psychotic decompensation. As in previous reports it was marked polydipsia that precipitated the water intoxication, and they noted that the psychosis did not improve after correction of the hyponatremia alone.
We have observed a 56-year-old man with a childhood history of meningitis, with residual abducens palsy and mild presenile dementia of uncertain duration, who presented twice in 4 months with acute organic psychosis associated with inappropriate secretion of antidiuretic hormone.
OLSON ND. Water Intoxication and Psychosis. Ann Intern Med. 1974;80:279–282. doi: 10.7326/0003-4819-80-2-279_3
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Published: Ann Intern Med. 1974;80(2):279-282.
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