JOHN G. DEMAKIS, M.D.; ALOYSIUS PROSKEY, M.D.; SHAHBUDIN H. RAHIMTOOLA, M.B., F.R.C.P., F.A.C.P.; MOHAMMED JAMIL, M.D.; GEORGE C. SUTTON, M.D., F.A.C.P.; KENNETH M. ROSEN, M.D.; ROLF M. GUNNAR, M.D., F.A.C.P.; JOHN R. TOBIN JR., M.D., F.A.C.P.
Fifty-seven patients with cardiomyopathy associated with alcoholism were followed for an average of 40.5 months (range, 4 months to 8 years). None of the patients were treated with prolonged bed rest. During the follow-up period, the clinical status improved in 15 patients (group A), was stable in 12 patients (group B), and had deteriorated in 30 patients (group C). Seventy-three percent of the group A patients abstained from alcohol, whereas in groups B and C only 25% and 13% of patients, respectively, abstained. These differences were significant—P < 0.03 (group A versus B) and P < 0.001 (group A versus C). The average duration of symptoms in the group A patients was 4.2 months and was significantly (P < 0.05) shorter than that of patients in groups B and C (17 and 11.1 months, respectively). Only 10 patients (17%), all in group A, had a return of heart size to normal. Twenty-four patients (42%), all in group C, died in an average time of 36 months; thus, a short duration of symptoms before initiation of therapy and abstention from alcohol were associated with a more favorable course.
JOHN G. DEMAKIS, ALOYSIUS PROSKEY, SHAHBUDIN H. RAHIMTOOLA, MOHAMMED JAMIL, GEORGE C. SUTTON, KENNETH M. ROSEN, et al. The Natural Course of Alcoholic Cardiomyopathy. Ann Intern Med. 1974;80:293–297. doi: 10.7326/0003-4819-80-3-293
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Published: Ann Intern Med. 1974;80(3):293-297.
Cardiology, Tobacco, Alcohol, and Other Substance Abuse.
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