JULIO V. RIVERA, M.D.
To the editor: I read with interest Dr. Newcombe's letter (1), in which he suggests a relation, probably genetic, between gout and adult-type polycystic kidney disease. Virchow (2), in 1856, first suggested that uric acid and lime infarcts in the renal medullae were the cause of obstruction, which led to the formation of renal cysts. Although this theory is no longer tenable, it pointed to a relation between uric acid and polycystic disease. In 1965 we studied a family group in which these two conditions were associated in a way that suggested a genetic linkage (3). Six of 10 other
JULIO V. RIVERA. Gout and Polycystic Disease of Kidney. Ann Intern Med. 1974;80:427. doi: 10.7326/0003-4819-80-3-427_1
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Published: Ann Intern Med. 1974;80(3):427.
Gout, Nephrology, Rheumatology.
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