ANIL K. MANDAL, M.D., F.A.C.P.; DENNIS R. MASK, M.D.; JOHN NORDQUIST, B.S.; KATERINA S. CHRYSANT, M.D.; ROBERT D. LINDEMAN, M.D., F.A.C.P.
To the editor: Although numerous reports have been published on viral-like particles inside glomerular endothelial cells in collagen diseases (1-3), only rarely have such particles been found in the glomerular basement membranes in patients with nephrotic syndrome (4, 5). We report here finding numerous viral-like inclusion bodies within the glomerular basement membranes in two additional patients with nephrotic syndrome.
A 45-year-old white woman was admitted in 1968 with a 7-year history of intermittent swelling of the body. Laboratory studies showed a 24-hour urine protein excretion of 6.6 g, a serum albumin of 2.7 g/100 ml, and a serum
MANDAL AK, MASK DR, NORDQUIST J, CHRYSANT KS, LINDEMAN RD. Membranous Glomerulonephritis: Virus-Like Inclusions in Glomerular Basement Membrane. Ann Intern Med. ;80:554–555. doi: 10.7326/0003-4819-80-4-554
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Published: Ann Intern Med. 1974;80(4):554-555.
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