G. G. CORNWELL III, M.D.; L. R. ZACHARSKI, M.D.
To the editor: A 56-year-old man first sought medical attention in September 1970 for recurrent perineal ulcerations; he had no history of joint disease.
The spleen tip was palpable beneath the left costal margin. The hemoglobin was 8.3 g/100 ml, and the leukocyte count was 700/mm3, with 30% mature neutrophils, 14% stabs, 36% lymphocytes, 18% monocytes, and 2% eosinophils. The platelet estimate, Coombs' test, and serum protein electrophoresis were normal. The bone marrow was hypercellular, with increased eosinophils and marked reduction in segmented neutrophils; iron stores were absent. The rheumatoid factor was positive in a dilution of 1 to 5120.
CORNWELL GG, ZACHARSKI LR. Neutropenia, Elevated Rheumatoid Factor, Splenomegaly, and Absence of Rheumatoid Arthritis. Ann Intern Med. ;80:555–556. doi: 10.7326/0003-4819-80-4-555
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Published: Ann Intern Med. 1974;80(4):555-556.
Rheumatoid Arthritis, Rheumatology.
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