HARVEY B. SIMON, M.D.; SHELDON M. WOLFF, M.D.
To the editor: In their report of "Hepatic Granulomatosis and Sarcoidosis" (1), Drs. Israel and Goldstein provide a useful reminder that sarcoidosis can involve the liver, or indeed other organs, without presenting intrathoracic abnormalities. They also clearly recognize that many diverse processes can produce hepatic granulomata and that in many patients the diagnosis remains obscure. Of their 30 cases, only 9had features allowing a clear diagnosis of sarcoid, whereas 6 had "probable" sarcoidosis; in two patients Hodgkin's disease appeared to account for the granulomata, and in the remaining 13 patients the diagnosis was "undetermined," despite careful study.
We have recently
SIMON HB, WOLFF SM. Sarcoidosis and Hepatic Granulomatosis. Ann Intern Med. ;80:560–561. doi: 10.7326/0003-4819-80-4-560_2
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Published: Ann Intern Med. 1974;80(4):560-561.
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