PETER V. SACKS, M.D.; MEHDI TAVASSOLI, M.D., F.A.C.P.
To the editor: The encouraging paper by Dr. Grann and colleagues (1) on the results of treatment of acute granulocytic leukemia has a serious flaw; the failure to mention drug dosages. Although we realize that the data were accumulated retrospectively over a period covering a number of protocols, it would be important to know whether the doses of cytosine arabinoside and thioguanine given to the "elderly" patients, after 1969, equaled those given to the "younger" patients. Is it possible that the excellent remission rates in these elderly patients reflects a "tempered" approach with delivery of significantly less than the projected
SACKS PV, TAVASSOLI M. Leukemia in the Elderly. Ann Intern Med. ;81:133. doi: 10.7326/0003-4819-81-1-133_1
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Published: Ann Intern Med. 1974;81(1):133.
Geriatric Medicine, Hematology/Oncology, Leukemia/Lymphoma.
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