T. K. SREEPADA RAO, M.D.; ANTHONY D. NICASTRI, M.D.; ELI A. FRIEDMAN, M.D.
To the editor: The study of glomerular focal sclerosis by Matalon and associates (1) adds further support to previous reports (2-5) indicating an association of heroin addiction and nephropathy. All 10 patients reported were black, whereas only 30% of hospital admissions to New York University were black. Five of these were male heroin addicts who had massive proteinuria and focal and segmental glomerular sclerosis. Except for Patient 4, whose renal function improved, all other patients showed deterioration of renal function.
These observations fit our description (2) of a syndrome of focal glomerular sclerosis, massive proteinuria, and azotemia in 14 black
RAO TKS, NICASTRI AD, FRIEDMAN EA. Heroin Addiction and Nephropathy. Ann Intern Med. ;81:416. doi: 10.7326/0003-4819-81-3-416_2
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Published: Ann Intern Med. 1974;81(3):416.
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